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席娜娜, 左宗力, 隆素素, 等.四川省绵阳市乙型肝炎病毒感染现况研究.四川大学学报(医学版),2017,48(1):101-106
四川省绵阳市乙型肝炎病毒感染现况研究
  
中文关键词:  现况研究 HBsAg 影响因素 Logistic回归
英文关键词:HBV infection HBsAg Influence factor Logistic model
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中文摘要:
      目的 了解绵阳市乙型肝炎病毒(简称乙肝病毒)感染流行现状及分布特点,分析影响人群感染乙肝病毒的因素,为开展有针对性的乙型肝炎(简称乙肝)防治、建立适合西部地区二级城市乡镇/社区乙肝防治模式提供理论依据。方法 对来自“十二·五”绵阳重大传染病综合防治示范研究中强化干预区的体检数据进行统计描述,并选用两水平logistic回归模型分析影响人群感染乙肝病毒的因素。结果 绵阳市一般人群的HBsAg携带率粗率为4.91%,HBsAg携带率在个体层面会随着个体年龄的增加而升高。乙肝病毒感染在乡镇水平存在聚集效应,其影响因素中丘陵地形、公共卫生支出100万元及以上属于保护因素;个人行为中,无外出3个月的经历、无输血史、无乙肝家族史、饮酒量小于20 g/d属于保护因素;年龄、男性、非医务工作者、无乙肝疫苗接种史、饮酒量大于80 g/天均属于危险因素。结论 绵阳市属于中地方性流行地区,但其下属仍有个别乡镇为高地方性流行地区;乙肝病毒感染存在地区聚集,传统的危险行为因素仍是影响个体感染乙肝病毒的关键。
英文摘要:
      Objective To determine the prevalence and distribution of hepatitis B virus (HBV) infection in Mianyang. Methods Data were extracted from the 12th five-year National Science and Technology Major Projects——Integrated Prevention and Control of Major Infectious Diseases in Mianyang. A two-level logistic regression model was established to determine factors associated with HBV infection. Results About 4.91% of people in Mianyang were HBsAg positive, which increased with age. HBV infection showed aggregation at townships. Governmental spending ≥¥1 000 000 on public health was a protective factor in the regression model; whereas, age, male gender, medical workers, absent from HBV vaccination, more than 80 g/d alcohol consumption were risk factors of HBV infection. Conclusion Mianyang had medium level of HBV infections. But high HBV prevalence can be found in some townships. The known behavior risk factors all exist in Mianyang, which can serve as a screening tool for identifying high risk populations.
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